Workshop
Biological Large Scale Integration
BioLSI-2
April 10–12, 2006
California Institute of Technology
Winnett Lounge
This workshop follows on the theme of the first BioLSI workshop held in Aspen, January 2004. BioLSI-2 will be a small "working meeting" focusing on universal challenges that currently confront the research community pursuing large-scale-integration of heterogeneous microfluidic systems and biosensors. BioLSI-2 will be kept small to insure a vibrant and open exchange of ideas. The registration fee for the workshop, including continental breakfasts, box lunches, and coffee breaks for the three days of the event is $250.
View info in pdf format:
On-line registration: Closed.
Speakers
Jessica
Arlett, Rashid
Bashir, Steve
Buchsbaum, Thomas Braun, Jason Cleveland, Eric
Eisenstadt, Alex
Groisman, Joseph
Hacia, Carl
Hansen, Jim
Heath, Jong
Wook Hong, Emil
Kartalov, Luke
Lee, Sebastian
Maerkl, Scott
Manalis,
Richard
Mathies, Adrian
Ozinsky,
Mark
Paul, Demetri
Psaltis, Steve
Quake, Michael
Roukes, Axel
Scherer, Christina
Smolke, Tom
Soh, Sandra
Troian, John
Wikswo, Changhuei
Yang.
Conference Organizers
Michael Roukes, Caltech
Stephen Quake, Stanford
Special thanks to Caltech's Beckman Institute.
Program
The format will be a series of half-hour presentations over three days that focus on state-of-the-art techniques, applications, and issues. Each presentation will be followed by up to a half hour of discussion. To facilitate lively and constructive interchange after each presentation, a separate moderator will join each speaker to stimulate the post-presentation discussion.
A non-exclusive list of possible topics includes:
- Microfluidics
- New polymeric materials for microfluidics
- Novel integrated actuation methods (e.g. beyond pneumatics)
- High volume/throughput techniques
- Techniques for extreme conditions (e.g. high temperatures & pressures, harsh chemistry)
- Theory and modeling of complex microfluidic systems
- Integration of complex, multi-step biochemical protocols
- Surface Chemistry at the Micro- and Nanoscale
- Microfluidic surface biopassivation & biofunctionalization
- Micro- and nanosensor biopassivation & biofunctionalization
- Routes to massively multiplexed biofunctionalization
- New approaches to high avidity analyte capture (aptamers, click-chemistry, minibodies)
- Stability/lability of surface chemistry (during storage & under conditions of real applications)
- Micro- and Nanoscale Biosensors
- Biophysics of analyte-capture transduction
- Novel biosensing techniques (novel signal transduction)
- Performance of sensors under real conditions (e.g. complex mixtures, serum)
- Metrics for sensing (e.g. dynamic range, sensitivity, selectivity, crosstalk…)
- Enhancement of analyte capture (e.g. dielectrophoretic or fluidic methods)
- Sensor array engineering (electrical and chemical sensor crosstalk, multiplex readouts)
- Heterogeneous Systems Integration
- Production Challenges
- Microsystems Bioinformatics
- Biophysics of stochastic analyte capture
- Signature detection
- Protocol for signal analysis (e.g. rejection of false positives)
- Biological Applications
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